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    • Is C-reactive Protein an Independent Risk Factor for Complication of Laparoscopic Cholecystectomy for Acute Cholecystitis?

    Hamdy A. Elhady
    Department of General Surgery ,Tanta University

    Background: Acute cholecystitis (AC) is the most common complication of gall bladder stones. C-reactive protein (CRP) level is only used as a diagnostic criterion of AC. Because there is the lack of studies demonstrating abetter discrimination power of CRP measurement on AC, The aim of this study was evaluate the discriminative power of CRP in AC management and treatment outcome. Patients and Methods: The number of patients in this study was 30 patients presented with AC. After clinical examination, Laboratory and radiological investigations and resuscitation within 1st 24h. of admission, all patients treated by laparoscopic cholecystectomy (LC). Results: Out of total participants, 8 patients were males (26.7%) and 22 females (73.3%). There ages ranged from 21 to 66 years with mean ± SD 11.29. Higher levels CRP were found in cases of high grade fever, palpable tender right. hypochondrial mass and pyocele cases with significant difference which was 0.001, 0.001 and 0.005 respectively.Timing of intervention was within 7 days from 1st symptom day ranged 2-7 days with mean 4.37.Total operative time was ranging from 42-180 minutes with a mean of 109.57 minutes.Blood loss ranged from 50-200 cc with mean 95.Total hospital stay ranged from 4-6 days. Conclusion: High levels of CRP with male sex, high grade fever preoperatively, presence of palpable tender right. hypochondrial mass, high total leucocytic count, cases of pyocele and presence of intra-operative adhesion and timing of intervention are risk factors for difficulty, complications, operative and postoperative out come in patients under going laparoscopic cholecystectomy for Acute cholecystitis. 

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