Background: Creation of the pneumoperitoneum is the first and most critical step of a laparoscopic procedure because that access is associated with injuries to the gastrointestinal tract and major blood vessels and at least 50% of these major complications occurs prior to commencement of the intended surgery. This complication rate has remained the same during the past 25 years. Objective: To focus on the safety of the most used methods of entry into the peritoneal cavity in laparoscopic surgery with particular attention to patients submitted to previous surgery without comorbidities. Patients and Methods: Types of studies: prospective study. This study was conducted at Ain Shams university Hospital and El-Minia University Hospital in the duration from January 2018 till July 2018. The studied cases were divided in four groups of ten patients each comparing between different techniques of laparoscopic port entry in the abdominal wall: Group (A): open technique Group (B): visiport technique. Group (C): veress needle technique Group (D): closed entry technique. Results: We compared between different techniques of laparoscopic entry (Open-entry technique, Veress Needle entry, Direct-vision entry, closed entry technique). Our study reported no events of failed entry in different groups of laparoscopic port entry techniques. Conclusion: Overall, there is insufficient evidence to recommend one laparoscopic entry technique over another. More studies are required with larger sample size to determine the safer technique of laparoscopic port entry in the abdominal wall.