Background : Laparoscopic sleeve gastrectomy is one of the most commonly performed procedures for treatment of morbid obesity. Staple line reinforcement was recommended by many bariatric surgeons in order to reduce early post operative complications related to the staple line as bleeding and leakage. Aim of work : Studying the impact of staple line invagination during laparoscopic sleeve gastrectomy on the incidence of bleeding and leakage and on gastric pouch volume in the early post operative period. Patients and Methods : Laparoscopic sleeve gastrectomy was performed in 145 morbidly obese patients who were classified randomly into 2 groups; group A : includes 58 patients with invagination of the staple line by continuous absorbable sutures (3-0 vicryl) and group B : 87 patients without invagination of the staple line. Results : There is no effect of stable line invagination on the incidence of bleeding or leakage or on the gastric pouch volume measured by CT volumetry 1 month post operatively. Higher BMI ≥49.7 kg/m2 is associated with increased probability of bleeding incidence in patients with invagination of the staple line. Also, male gender were associated with increased incidence of bleeding, while the patients’ ages or the presence of co-morbidities were not affecting the incidence of bleeding. Conclusion: There is no significant difference between the two techniques on the incidence of bleeding and leakage and on gastric pouch volume. Incidence of staple line bleeding was higher in male patients and in cases with BMI ≥49.7 kg/m2 in patients underwent invagination of the staple line. Keywords: Morbid obesity, bariatric surgery, laparoscopic sleeve gastrectomy, staple line invagination, staple line, reinforcement, gastric pouch volume.