Hatem Elsahar, Khaled Sadek, Waleed Elmoez Reda
Khaled Sadek, Dawlat Emara, Hatem Elsahar, Waleed Elmoez Reda, Moamem Fayez Sarameejo
1Sameh A. A. Mikhail, 2Nader S. Zaki, 3Tamer M. Nabil
Shaimaa Mostafa1, Waleed E Reda1, Hamed M Kadry1, Amr A Zaky1,Mohamed A Hussein1, Karim M Mousa2
Abdulrahman Mohamed Salem1& Fouad S Fouad2
Mohammed Matar, Fady Makram, Wadie Boshra
Mohammed Matar, Fady Makram, Gamal Fawzy
Mohamed Mahfouz, Ahmed Hussein Abdelhafez
Ahmed Hussein Abdelhafez, Mohamed Mahfouz
Amr Saleh Elbahaey, Hossam Zaghloul Yousuf, Haitham A.Eldmarany
Mohammed H. Eldessoki 1, Haitham A.Eldmarany 2, Ahmad Gamal1
Youssif Khachaba, Tarek Ashour, Laila Aboul Nasr, Sherif Zamer
1Ahmed M.S.M Marzouk, 2Heba O.E Ali
1Sameh Mikhail, 2Khoweiled Abd ElHalim, 1Mohamed Hassan
1Waleed AlBadry, MSc, MRCS; 1Raafat Gohar, MD; 1Ashraf El-Sebaie, MD; 2Mohamed Salah, MD; 1Mohamed Ashraf El Meleigy, MD
Comparative Study between Duodeno-jejunal Bypass and Ileal Transposition (DJB &IT) in Management of Type II Diabetes Mellitus (DM) in Obese Patients with BMI 30-35
Background: The prevalence of obesity and T2DM has increased dramatically worldwide, becoming a
serious global public health problem. Bariatric surgery should be considered as an alternative line for
treating patients with a BMI of 30–35 kg/m2 when DM cannot be controlled by medical regimen.With the
exception of omentectomy, which has proven to be totally ineffective, the newly developed operations
specifically designed for T2DM treatment ' duodeno-jejunal bypass and ileal transposition (DJB &IT) were
inspired by the two known hypothesis (hindgut & foregut theory). Patients and methods: A prospective
randomized control trial study at Ain-shams university hospital using the closed envelop method was held
at Ain Shams university hospitals, from February 2014 up to July2016 upon 40 obese patients with BMI
between 30-35sufferring from type II DM comparing duodeno-jejunal bypass and ileal transposition
regarding their effect on glycemic control. Results: In this study, the 20 patients who had DJB, the mean
FBG decreased from 257 mg/dl to 106 mg/dl, and the 2H-PP value also decreased from 335 mg/dl to 161
mg/dl with improvement of HbA1c from 9 gm% to 5.7 gm%. The S. insulin level increased from 9.8 miu/ml
to 12.4 miu/ml , with associated increased C-Peptide from 0.9 ng/ml to 1.2ng/ml.In the 20 patients who had
ITthe FBG decreased from 265 mg/dl to 92 mg/dl, and the 2H-PP value also decreased from 347 mg/dl to
143 mg/dl with improvement of HbA1c from 8.8gm% to 5.4gm%. The S. insulin level increased from
9.6miu/ml to13.6 miu/ml, with associated increased C-Peptide from 0.9ng/ml to 1.4ng/ml. Conclusion:
These data provide preliminary evidence about the benefits of metabolic surgery on the glycemic control of
T2DM obese subjects with a BMI of < 35 kg/m2.However, more randomized controlled trials are needed to
investigate the effects of surgery in T2DM remission in pre-obese patients.