Mohamed Farouk, M.D.* and Wael Naeem Thabet Aziz, M.D.**
Mohamed Farouk, M.d.* and Wael Naeem Thabet Aziz, M.D.**
Haitham Akram Saimeh
Haitham Akram Saimeh
Mohamed Hamed Abouelfadl, MD. (1), Mahmoud M. Marei, MD. (1), Moutaz Ragab, MD(1), Ahmed Arafa Elsayed Rawash, MD. (1), Wesam Mohamed Mahmoud, MD. (1), Siham Anwer Imam, MD.(1&2), Ahmed Abdelhaseeb Youssef, MD(3), Tamer Yassin Mohamed Yassin, MD. (1)
Ashraf Kamal Abdalla, M.D. * ; Amr Mohamed EL Hefny, M.D.* ; Khaled Ahmed Reyad, M.D.** ; Noura Omar Mohamed, M.B.B.CH. **;
Sherif M. Mokhtar, Hasan Abouelnaga, Wael Lolah, Salma Dowara, Emad Khallaf
Ali Mohamed. A. Saleh , M.D ,CAIRO *, Arafat Ali Mohammed Al-absi , M.B.B.Ch
Sherif M. Mokhtar, HasanAbouelnaga, Wael Lolah, Salma Dowara, Emad Khallaf
Ahmed Maher AbdElmonim, RehamEltatawy, Ayman S. El-Din Helmy, Mohamed Hassan Ali Fahmy, Mohammed Elshal
Ahmed Qasem Mohamed,1 Essam Eldeen M.O. Mahran2
Hosam El Dein Said Hesain
Ramy Mikhael Nageeb,1 Hatem ElGohary, MD;2 Mohamed Gamal, MD3
Mohamed Saber Mostafa, Mohamed Elsayed Elshaaer, Aly Elshehry
Ahmed Samir Hosny, MD; El-Sayed A. Abd El-Mabood, MD; Amro Abdel Reheem, MD
Can intraoperative parathyroid hormone (IOPTH) assay replace combined IOPTH and frozen section in Parathyroidectomy for 1ry hyperparathyroidism: A comparative study?
Introduction: Primary Hyperparathyroidism (PHPT) is caused by single adenoma in most of the cases and surgery is the only curative management till now. Routine frozen section was and still an important operative step for many surgeons but with the introduction of highly accurate preoperative localization with sestamibi scan and available IOPTH assay, can surgeons skip this step? Objectives: Comparing IOPTH alone versus combined IOPTH and frozen section for detecting successful parathyroidectomy in cases of primary hyperparathyroidism. Patients and methods: Forty patients with primary hyperparathyroidism and indicated for parathyroidectomy were divided into 2 groups, Group A had only IOPTH assay while group B had both IOPTH and frozen section for parathyroid tissue confirmation. Results and conclusion: The 2 groups had similar features regarding demographics. The mean time for receiving FS results was statistically highly significant when compared with IOPTH mean time (P value less than 0.0001). Those results were consistent with those resulting from calculating the total operative time in both groups which were undoubtfully and statistically in favor of IOPTH alone group. IOPTH assay when available could alone guide intraoperative decision-making during parathyroidectomy surgeries. Disclosure: This article is not sponsored by any company, so the authors have no competing interests as defined by Nature Publishing Group, or other interests that might be perceived to influence the results and/or discussion in this article.
Keywords: Primary Hyperparathyroidism, intraoperative parathyroid hormone assay, parathyroidectomy, frozen section.