Objective: is to present our experience in making benefit of endovascular angioplasty techniques to insert chronic venous catheter (CVC) in hemodialysis patients who suffer obstruction or stenosis of central veins. Patient and methods: Eight patients on regular hemodialysis for long time and have consumed arteriovenous fistulae (AVF) and graft (AVG) were included. All patients strived to have an adequate access for their hemodialysis that either was not possible due to their co-morbidities or obstructed central veins. The earlier made any surgical intervention risky and the latter prevented insertion of CVC. We could recanalize the central veins by balloon angioplasty and be able to insert CVC down to the right atrium in five patients. Two patients have had their CVC inserted through the common femoral vein (CFV) after being dilated by balloon. The remaining patient had been tried in vain crossing the obstruction in both innominate vein and superior vena cava. Consequently, a CVC was inserted into the left CFV. Conclusion: insertion of CVC in patient who consumed all available AVF & AVG particularly in whom repeated insertion and exchange of CVC were done, can be challenging owing to limitation of available veins. In such situation, catheter insertion should be done with all facilities available to perform angioplasty whenever required. Key words: central veins, venous obstruction, balloon angioplasty, endovascular, hemodialysis access, chronic venous catheter.