Hisham Khalifa MD1, Ahmed Touny MD1 , Ihab Saad1 , Ahmed Abd elmaabood2 , Iman Hussein3 , Sherif Maamoon1
Mohamed Abd El-Moneim El-Masry(MD); Muhammad El Marzouky (MD); Yehia Fayez (Msc)
Ahmed M.S.M. Marzouk MD, Hany M.S. Mikhail MD, Abdrabou N Mashhour MD, Emad Fathi MSC
Mohamed Abd El-Moneim El-Masry(MD); Hussein Oukasha(MD)
Mohamed El-Maadawy, MD & Amr Abdelraheem, MD.
Mohamed I Abdelaziz, MD, Salah S. Soliman,MD, Hany F Habashy
Wael L. Tobar, A Ayad MD, A Morad* MD
Haidy N. Ashem MD. and Mohamed Yehia MD.
Ahmed Touny MD, Amr Selim. MD
Ayman M. A. Ali MD. & Ahmed Gaber Mahmoud MD
Ahmed Ali Ebrahiem Ali, M.Sc.
Amr Ibrahim Fouad (MD), Ashraf AbolFottoh (M), Sameh El Noamany Mohamed Hazem (MD)
Ahmed Samir Hosny.M.D.MRCS (Ed); Mohamed El Maadawy. M.D
Waheed Yousry Gareer MD, Mohamed El-Sayed Safa MD, Amr Seliem MD
Idiopathic Granulomatous Mastitis: Is a Challenging Disease
Idiopathic granulomatous mastitis (IGM) is a rare benign disease of uncertain etiology having diagnostic
and therapeutic challenges which was treated surgically with poor outcome. This study tried to clarify the
diagnostic difficulties and to evaluate different lines of treatment and their outcomes. This is a prospective
study randomly included 9 patients with proven IGM based on clinical, radiological and pathological
examinations. The outcome of diffferent treatment options was evaluated after a mean follow-up period of
18.9±2.1 months. All patients presented with a history of a unilateral painful palpable breast lump.
Patients had a clinical presentation mimic inflammation in (56%) and malignancy in (44%).
Histopathology was conclusive in exclusion of other causes of granulomas thus diagnosing IGM while
ultrasonography and mammography was not. Eight cases out of nine responded to corticosteroid therapy
(mean 3.5 months) while one was resistant and responded to surgical excision. At follow-up (22%) had
recurrence and responded well to a second course of corticosteroid. Conclusion. A combination of surgery
and medical treatment for IGM according to the severity is better than any alone.
Keywords: Granulomatous lobular mastitis, corticosteroid treatment, Breast Carcinoma.