Aim of the Study: To evaluate our centers results of both techniques, radiofrequency and endo-venous laser ablation of varicose veins as regard the efficacy and rate of complications. Material & Methods: This study was designed as a prospective analysis of the two techniques for varicose veins treatment that was done from January 2012 to December 2015. This study included two groups of patients, one Group A (151 patients) who were exposed to endo-venous laser ablation (EVLA) and Group B (167 patients) in whom radiofrequency ablation was done. We studied both techniques with regards post-operative pain degree, post-operative thrombophlebitis & DVT and the rate of recurrence within one year. Results: The primary closure of both techniques was 100%. The postoperative pain in the first two weeks were significantly higher in group A (33/151= 21.8%) than in group B (12/167 = 7.1%), however this difference is not significant after those two weeks. Also three weeks post-operative, thrombophlebitis rate was significantly higher at group A (17/151 = 11.2%) than group B (4/167 = 2.3%). No DVT was detected in both groups, while the rate of recurrence of SFJ reflux within one year follow up was 1.3% (2/151) & 4.1% (6/167) in groups A & B respectively. Conclusion: RFA using VNUS® Closure FAST™ was associated with less post procedural pain & thrombophlebitis than EVLA. However, clinical and quality-of-life improvements were similar after 2 weeks for the two treatments. The efficacy of both techniques was the same as regard the vein closure without recanalization within one month follow up. The regional nerve block technique for anesthesia is effective & safe method for endo-venous ablation. Key Words: Radiofrequency, Laser albation, Saphenous reflux.