Chronic kidney disease is a major public health problem. Hemodialysis is still the most commonly used form of renal replacement therapy . Arteriovenous fistulae are the preferred mode of vascular access worldwide due to its ability to provide high blood flow rates with superior patency and low rate of complications. Vascular access failure is a major source of morbidity, mortality and expense for patients undergoing hemodialysis. Every effort should be spent to preserve them as their value can only become more precious the longer the patient remains on hemodialysis. Several techniques have been described to maintain a hemodialysis access site; varying from open surgical ones to percutaneous endovascular approaches and sometimes hybrid procedures. Patients and Methods: This study included 20 patients who were referred from the dialysis unit to vascular surgery department of kasr alainy hospitals in the period between march 2012 to march 2014 with dysfunctional arteriovenous fistula. All of the patients underwent fistulography followed by angioplasty and they were followed up for 6 months. Results: The age of patients ranged from 27 to 79 years. The study included 14 males and 6 females. Our study included 10 radiocephalic AVF , 4 brachiocephalic AVF, and 6 brachiobasilic AVF with superficialization. Transradial approach was used in 16 patients of which cutdown technique was applied in 6 cases due to very distal AV fistula. Transvenous approach was used in 4 cases.Juxta-anastomotic venous stenosis was detected in the 16 cases. Multiple stenoses in the draining vein were detected in 4 cases. Associated Arterial stenosis was detected in 4 cases. Angioplasty was performed in all patients. Technical success was 18/20 cases. One vein ruptured and resulted in a hematoma and the fistula was surgically ligated and the other there was failure of angioplasty. One radial access hematoma occured and was managed conservatively. Conclusion: PTA is an effective therapy in restoring the function of failing AVFs. Compared to surgery, PTA has several advantages, including the fact that it is relatively simple, less invasive, shorter procedure, causes less stress to the patient, enables immediate dialysis without the need for central venous catheter, reduces the risk of infection, and saves the patient’s veins. Keywords : Salvage of AV fistula, fistula angioplasty.